CASQ1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52513
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | Calmitin,Calmitine,Calsequestrin 1 (fast twitch, skeletal muscle),Calsequestrin,Calsequestrin, cell,Calsequestrin, skeletal muscle isoform,Calsequestrin-1,CASQ,Casq1,CASQ1,PDIB1,skeletal muscle isoform,CASQ1抗体 |
Swissprot | P31415 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human CASQ1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:300 |
Concentration | 1.6mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Sarcoplasmic reticulum lumen. Mitochondrion. This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Also mitochondrial according to PubMed:7945294. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes the skeletal muscle specific member of the calsequestrin protein family.Calsequestrin functions as a luminal sarcoplasmic reticulum calcium sensor in both cardiac and skeletal muscle cells.This protein, also known as calmitine, functions as a calcium regulator in the mitochondria of skeletal muscle.This protein is absent in patients with Duchenne and Becker types of muscular dystrophy. |