CBX3 Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22270
宿主: Mouse
反应性: H,M,R
应用: WB,IHC-p
Overview
| Synonyms | CBX 3,CBX3,CBX3,Chromobox homolog 3 (HP1 gamma homolog,Drosophila),Chromobox homolog 3,Chromobox protein homolog 3,GAMMA,HECH,Heterochromatin like protein 1,Heterochromatin protein 1 homolog gamma,Heterochromatin protein HP1 gamma,HP1 gamma,HP1 gamma homolog,HP1Hs gamma,Modifier 2 protein,HP-1γ Mouse (4F4)抗体 |
| Swissprot | Q13185 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Protein of HP-1γ |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-2000;IHC,,1:50-300; |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Nucleus. Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis. |
| Clone No | Clone:4F4 |
|---|---|
| Isotype | IgG |
| Purification | Protein A purification |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Background | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane.The protein encoded by this gene binds DNA and is a component of heterochromatin.This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane.The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.This protein binds histone H3 tails methylated at Lys-9 sites.This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. |
Images
Western Blot analysis of 1) Hela, 2) 3T3, 3) PC12 cells using CBX3 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human colon carcinoma tissue using CBX3 Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Human placenta tissue using CBX3 Monoclonal Antibody at dilution of 1:200.
