CBY1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10937
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | ARPP-binding protein,C22orf2,CBY,Cby1,CBY1,Cytosolic leucine rich protein,Cytosolic leucine-rich protein,Golgi and endoplasmic reticulum-associated 1,HRIHFB2025,PIGEA 14,PIGEA-14,PKD2 interactor,PKD2 interactor,Golgi and endoplasmic reticulum-associated 1,Protein Chibby,Protein chibby homolog 1,CBY1抗体 |
| Swissprot | Q9Y3M2 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human CBY1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus speckle. Golgi apparatus, trans-Golgi network. Nuclear, in a punctate manner. Also found in the trans-Golgi. |
| Tissue specificity | Widely expressed. Expressed at higher levels in heart, skeletal muscle, kidney and placenta. Also found in brain, lung, liver and testis. Significantly down-regulated in thyroid and metastatic uterine tumors. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. |
