CCL27 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17773
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | ALP,C-C motif chemokine 27,CC chemokine ILC,Ccl27,CCL27,Chemokine (C-C motif) ligand 27,CTACK,CTAK,Cutaneous T cell attracting chemokine,Cutaneous T-cell-attracting chemokine,ESkine,IL 11 R alpha locus chemokine,IL-11 R-alpha-locus chemokine,ILC,PESKY,SCYA27,Skinkine,Small inducible cytokine A27,small inducible cytokine subfamily A (Cys-Cys),member 27,Small-inducible cytokine A27,CCL27抗体 |
Swissprot | Q9Y4X3 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human CCL27 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:300 |
Concentration | 1.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. CCL27 (C-C Motif Chemokine Ligand 27) is a Protein Coding gene. Diseases associated with CCL27 include Dermatitis and Atopic Dermatitis. Among its related pathways are Peptide ligand-binding receptors and PEDF Induced Signaling. GO annotations related to this gene include chemokine activity. An important paralog of this gene is CCL28. |