CCL5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17864
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Beta chemokine RANTES,Beta chemokine RANTES precursor,C C motif chemokine 5,CCL 5,CCL5,CCL5,Chemokine (C C motif) ligand 5,Chemokine CC Motif Ligand 5,D17S136E,EoCP,Eosinophil chemotactic cytokine,MGC17164,RANTES(4-68),Regulated upon activation normally T expressed and presumably secreted,SCYA 5,SCYA5,SIS delta,SIS-delta,SISd,Small inducible cytokine A5 (RANTES),Small inducible cytokine A5,Small inducible cytokine subfamily A (Cys Cys) member 5,Small-inducible cytokine A5,T cell specific protein p288 ,T cell specific RANTES protein,T cell-specific protein P228,T-cell-specific protein RANTES,TCP 228,TCP228,CCL5抗体 |
| Swissprot | P13501 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human CCL5 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. |
