CCR5 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70361
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | AM4 7,C C chemokine receptor type 5,C C CKR 5,C-C chemokine receptor type 5,C-C CKR-5,C-C motif chemokine receptor 5 A159A,CC Chemokine Receptor 5,CC Chemokine Receptor Type 5,CC CKR 5,CC-CKR-5,CCCKR 5,CCCKR5,CCR 5,CCR-5,CCR5,CCR5 chemokine (C C motif) receptor 5,CCR5,CD 195,CD195,CD195 Antigen,Chemokine C C motif receptor 5,Chemokine receptor CCR5,CHEMR13,CKR 5,CKR5,CMKBR 5,CMKBR5,FLJ78003,HIV 1 Fusion Coreceptor,HIV-1 fusion coreceptor,HIV1 fusion coreceptor,IDDM22,MIP-1 alpha receptor,CCR5抗体 |
| Swissprot | P51682,O08556 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CCR5 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 0.55 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Tissue specificity | Highest expression level in bone marrow macrophage |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. |
Images
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CCR5 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat spleen using CCR5 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat thymus using CCR5 Polyclonal Antibody at dilution of 1:300.
