CD14 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70113
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | CD 14,CD_antigen=CD14,CD14,CD14 antigen,CD14 molecule,CD14,LPS-R,Mo2,Monocyte differentiation antigen CD14,Monocyte differentiation antigen CD14 urinary form,Monocyte differentiation antigen CD14,membrane-bound form,Myeloid cell specific leucine rich glycoprotein,Myeloid cell-specific leucine-rich glycoprotein,CD14抗体 |
| Swissprot | P08571,P10810,Q63691 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CD14 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:200-1:800; |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm,Membrane |
| Tissue specificity | Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. Highest expression level in liver. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | CD14 is a 50-55 kDa glycosylphosphatidylinositol-anchored glycoprotein. CD14 is preferentially expressed on monocytes and macrophages. CD14 acts as a co-receptor (along with TLR4 and MD-2) for bacterial liposaccharides (LPS). It plays a major role in the inflammatory response of monocytes to LPS. |
