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CD160 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14838

宿主: Rabbit

反应性: H

应用: WB,IHC

  • 详情
  • Overview

    Synonyms BY55,BY55,CD160,CD160 antigen [Precursor],CD160 antigen,CD160 delta Ig,CD160 molecule,CD160 transmembrane isoform,FLJ46513,Natural killer cell receptor BY55,Natural killer cell receptor,immunoglobulin superfamily member,NK1,NK28,CD160抗体
    Swissprot O95971
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human CD160
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:50-1:200;
    Concentration 0.7 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane.
    Tissue specificity Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55.Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity.The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule.CD160 is expressed at the cell surface as a tightly disulfide-linked multimer.RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine.
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