CD218b Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-14440
宿主: Rabbit
反应性: H,M
应用: WB
Overview
Synonyms | IL18RAP,Accessory protein like,Accessory protein-like,AcPL,CD218 antigen-like family member B,CD218b,CDw218b,I18RA,IL 18RAcP,IL 1R accessory protein like,IL 1R7,IL 1RAcPL,IL-18 receptor accessory protein,IL-18R-beta,IL-18RAcP,IL-18Rbeta,IL-1R accessory protein-like,IL-1R-7,IL-1R7,IL-1RAcPL,IL18RAP,IL18Rbeta,Interleukin 18 receptor accessory protein,Interleukin-1 receptor 7,Interleukin-18 receptor accessory protein,Interleukin-18 receptor accessory protein-like,Interleukin-18 receptor beta,Interleukin-18 receptor beta chain,IL18RAP抗体 |
Swissprot | O95256 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Recombinant protein of human IL18RAP |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Tissue specificity | Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiationw218b), is a human gene.The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18.This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor.The coexpression of IL18R1 and this protein is required for the activation of NF-κB and MAPK8 (JNK) in response to IL18. |