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CD218b Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14440

宿主: Rabbit

反应性: H,M

应用: WB

  • 详情
  • Overview

    Synonyms IL18RAP,Accessory protein like,Accessory protein-like,AcPL,CD218 antigen-like family member B,CD218b,CDw218b,I18RA,IL 18RAcP,IL 1R accessory protein like,IL 1R7,IL 1RAcPL,IL-18 receptor accessory protein,IL-18R-beta,IL-18RAcP,IL-18Rbeta,IL-1R accessory protein-like,IL-1R-7,IL-1R7,IL-1RAcPL,IL18RAP,IL18Rbeta,Interleukin 18 receptor accessory protein,Interleukin-1 receptor 7,Interleukin-18 receptor accessory protein,Interleukin-18 receptor accessory protein-like,Interleukin-18 receptor beta,Interleukin-18 receptor beta chain,IL18RAP抗体
    Swissprot O95256
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Recombinant protein of human IL18RAP
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.3 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Tissue specificity Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiationw218b), is a human gene.The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18.This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor.The coexpression of IL18R1 and this protein is required for the activation of NF-κB and MAPK8 (JNK) in response to IL18.
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