CD328 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-13120
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | Adhesion inhibitory receptor molecule 1,Adhesion inhibitory receptor molecule 1,siglec 7,AIRM 1,AIRM-1,AIRM1,CD328,CD328 antigen,CDw328,D siglec,D-siglec,HLDA 8,p75,p75/AIRM1,QA79,QA79 membrane protein,Sialic acid binding Ig like lectin 7,Sialic acid binding immunoglobulin like lectin 7,Sialic acid-binding Ig-like lectin 7,SIGL7,Siglec-7,SIGLEC19P,SIGLEC7,SIGLECP2,SIGLEC7抗体 |
Swissprot | Q9Y286 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human SIGLEC7 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Tissue specificity | Predominantly expressed by resting and activated natural killer cells and at lower levels by granulocytes and monocytes. High expression found in placenta, liver, lung, spleen, and peripheral blood leukocytes. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Sialic acid-binding Ig-like lectin 7 is a protein that in humans is encoded by the SIGLEC7 gene.SIGLEC7 has also been designated as CD328 (cluster of differentiation 328).Putative adhesion molecule that mediates sialic-acid dependent binding to cells.Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid.Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide).The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Images
Western Blot analysis of A549 cell using CD328 Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human liver cancer using CD328 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CD328 Polyclonal Antibody at dilution of 1:50