CD40 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16318
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | AI326936,B cell associated molecule CD40,B cell surface antigen CD40,B cell-associated molecule,B-cell surface antigen CD40,Bp50,CD 40,CD40,CD40 antigen (TNF receptor superfamily member 5),CD40 antigen,CD40 molecule,CD40 molecule,TNF receptor superfamily member 5,CD40 protein,CD40 type II isoform,CD40L receptor,CDw40,GP39,HIGM1,IGM,IMD3,MGC9013,Nerve growth factor receptor related B lymphocyte activation molecule,OTTHUMP00000031699,OTTHUMP00000031700,p50,T-BAM,TBAM,TNF receptor superfamily member 5,TNFRSF5,TNR5,TRAP,Tumor necrosis factor receptor superfamily,member 5,Tumor necrosis factor receptor superfamily member 5,Tumor necrosis factor receptor superfamily member 5 precursor,Tumor necrosis factor receptor superfamily,member 5,isoform CRA_a,CD40抗体 |
| Swissprot | P25942 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human CD40 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 1.3mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. |
| Tissue specificity | B-cells and in primary carcinomas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily.This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, whicHuman, Mouseay be important for homotypic cell interactions.Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction.The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. |
客户发表文献
- 文献: The immunostimulatory activity of polysaccharides from Glycyrrhiza uralensis
样品类型: Tissue homogenate
