CD45 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70024
宿主: Rabbit
反应性: M
应用: IHC
Overview
| Synonyms | B220,CD 45,CD45,CD45 antigen,CD45R,GP180,L-CA,LCA,Leukocyte common antigen,loc,Ly-5,LY5,Ly5,homolog of,Lyt-4,OTTHUMP00000033813,OTTHUMP00000033816,OTTHUMP00000033817,OTTHUMP00000038574,Protein tyrosine phosphatase receptor type c polypeptide,Protein tyrosine phosphatase,receptor type C,protein tyrosine phosphatase,receptor type,C,Protein tyrosine phosphatase,receptor type,c polypeptide,Ptprc,PTPRC,Receptor-type tyrosine-protein phosphatase C,T200,T200 glycoprotein,T200 leukocyte common antigen,CD45抗体 |
| Swissprot | P06800 |
| Source | Rabbit |
| Reactivity | Mouse |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CD45 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:500-1:1500 |
| Concentration | 1.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Membrane |
| Tissue specificity | Highest expression level in spleen |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | CD45,also known as leukocyte common antigen (LCA),B220,and T200,is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells,except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth,differentiation,cell cycle,and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. Along with the positive selection markers (such as CD29,CD44,CD90,CD105 and CD166),negative selection markers (such as CD34 and CD45) are used for MSC identification. |
Images
Immunohistochemistry analysis of paraffin-embedded mouse liver using CD45 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded mouse inflammatory spleen using CD45 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse lungs using CD45 Polyclonal Antibody at dilution of 1:1000.
