CD54 Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70046
宿主: Rabbit
反应性: H,M
应用: WB,IHC,IF
Overview
Synonyms | Antigen identified by monoclonal BB2,BB 2,BB2,CD 54,CD_antigen=CD54,CD54,Cell surface glycoprotein P3.58,Human rhinovirus receptor,ICAM 1,ICAM-1,ICAM1,ICAM1,intercellular adhesion molecule 1 (CD54),human rhinovirus receptor,Intercellular adhesion molecule 1,Major group rhinovirus receptor,MALA 2,MALA2,MyD 10,MyD10,P3.58,Surface antigen of activated B cells,BB2,CD54抗体 |
Swissprot | P05362,Q00238,P13597 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),IF |
Recommended dilution | WB,,1:1000-1:3000;IHC,,1:500-1:1000;IF,,1:200-1:800; |
Concentration | 0.84 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane |
Tissue specificity | Highest expression level in lung |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues . ICAM-1 is expressed by several cell types,typically on endothelial cells and cells of the immune system,and its expression can be up-regulated by various stimuli,including TNF-α,INF-γ,IL-1 and thrombin . It is a ligand for LFA-1 and Mac-1,serves as a receptor for rhinovirus,and is one of several receptors used by Plasmodium falciparum . |
Images
Western Blot analysis of various samples using CD54 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse kidney using CD54 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded Mouse liver using CD54 Polyclonal Antibody at dilution of 1:500.
Immunofluorescence analysis of paraffin-embedded mouse lung using CD54 Polyclonal Antibody at dilution of 1:300.