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CDC34 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-16330

宿主: Rabbit

反应性: H,M

应用: WB,IHC

  • 详情
  • Overview

    Synonyms Cdc 34,Cdc34,Cell division cycle 34,Cell division cycle 34 homolog (S. cerevisiae),Cell division cycle 34 homolog,E2 CDC34,UB2R1,UBC 3,UBC3,UBCH3,UBE2 R1,UBE2R1,Ubiquitin carrier protein,Ubiquitin conjugating enzyme Cdc34,Ubiquitin conjugating enzyme E2 32 kDa complementing,Ubiquitin protein ligase,Ubiquitin protein ligase R1,Ubiquitin-conjugating enzyme E2 R1,Ubiquitin-conjugating enzyme E2-32 kDa complementing,Ubiquitin-conjugating enzyme E2-CDC34,Ubiquitin-protein ligase R1,CDC34抗体
    Swissprot P49427
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Synthetic peptide of human CDC34
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:100-1:300;
    Concentration 0.6mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm. Nucleus. The phosphorylation of the C-terminal tail plays an important role in mediating nuclear localization. Colocalizes with beta-tubulin on mitotic spindles in anaphase.
    Tissue specificity Expressed in testes during spermatogenesis to regulate repression of cAMP-induced transcription.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.
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