CDC42BPA Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17780
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | A930014J19Rik,CDC42 binding protein kinase alpha (DMPK like),CDC42 binding protein kinase alpha,CDC42 binding protein kinase alpha dmpk like,CDC42 binding protein kinase beta,CDC42-binding protein kinase alpha,CDC42BPA,DKFZp686L1738,DKFZp686P1738,DMPK like,DMPK-like alpha,FLJ23347,KIAA0451,MGC189823,MRCK alpha,mrck,mrcka,MRCKA,Myotonic dystrophy kinase related CDC42 binding protein kinase alpha,Myotonic dystrophy kinase-related CDC42-binding kinase alpha,Myotonic dystrophy protein kinase-like alpha,OTTHUMP00000035727,OTTHUMP00000035728,OTTHUMP00000035729,OTTHUMP00000035730,pk428,RP5-1087E8.4,Ser thr protein kinase PK428,Ser thr protein kinase related to the myotonic dystrophy protein kinase,Serine/threonine protein kinase MRCK alpha,Serine/threonine-protein kinase MRCK alpha,CDC42BPA抗体 |
| Swissprot | Q5VT25 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human CDC42BPA |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 0.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. |
