CDCP1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13141
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | 9030022E12Rik,AA409659,CD 318,CD_antigen=CD318,CD318,CD318 antigen,CDCP 1,Cdcp1,CDCP1,CUB domain containing protein 1,CUB domain-containing protein 1,E030027H19Rik,FLJ13772,FLJ22375,FLJ22969,Membrane glycoprotein gp140,MGC31813,OTTHUMP00000164120,OTTHUMP00000209568,RGD1305578,SIMA 135,SIMA135,Subtractive immunization M plus HEp3 associated 135 kDa protein,Subtractive immunization M plus HEp3-associated 135 kDa protein,Transmembrane and associated with src kinases,TRASK,CDCP1抗体 |
| Swissprot | Q9H5V8 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human CDCP1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. Shedding may also lead to a soluble peptide. |
| Tissue specificity | Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. |
Images
Western Blot analysis of PC3 cell using CDCP1 Polyclonal Antibody at dilution of 1:1100
Immunohistochemistry of paraffin-embedded Human lung cancer using CDCP1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CDCP1 Polyclonal Antibody at dilution of 1:50
