CDK1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70286
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | Cdc 2,Cdc2,CDC28A,CDK 1,CDK1,CDK1,CDKN1,CELL CYCLE CONTROLLER CDC2,Cell division control protein 2,Cell division control protein 2 homolog,Cell division cycle 2 G1 to S and G2 to M,Cell division protein kinase 1,Cell Divsion Cycle 2 Protein,Cyclin Dependent Kinase 1,Cyclin-dependent kinase 1,DKFZp686L20222,MGC111195,p34 Cdk1,p34 protein kinase,P34CDC2,CDK1抗体 |
| Swissprot | P06493,P11440,P39951 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to mouse CDK1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 2.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, Cytoskeleton, Mitochondrion, Nucleus |
| Tissue specificity | Isoform 2 is found in breast cancer tissues.Highest expression level in intestine. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | CDK1, also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. CDC2 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. It is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. Mitotic cyclins stably associate with CDC2 and function as regulatory subunits. The antibody is specific to the 2 isoforms of CDC2. |
