CHAT Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70028
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | Acetyl CoA choline O acetyltransferase,Acetyl CoA:choline O acetyltransferase,Chat,CHOACTase,Choline acetylase,choline acetyltransferase,Choline O acetyltransferase,Choline O-acetyltransferase,CLAT,CMS1A,CMS1A2,EC 2.3.1.6,OTTHUMP00000019583,OTTHUMP00000019584,CHAT抗体 |
| Swissprot | P28329,Q03059,P32738 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CHAT |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:500 |
| Concentration | 350 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Nucleus,Other locations:cytoplasm,presynapse |
| Tissue specificity | Highest expression level in placenta |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. |
