CHOP Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22243
宿主: Mouse
反应性: H,M,R
应用: IHC-p
Overview
| Synonyms | C/EBP homologous protein,C/EBP Homology Protein,C/EBP zeta,C/EBP-homologous protein 10,C/EBP-homologous protein,CCAAT/enhancer binding protein homologous protein,CEBPZ,CHOP 10,CHOP,CHOP-10,CHOP10,DDIT 3,DDIT-3,Ddit3,DDIT3,DNA Damage Inducible Transcript 3,DNA damage-inducible transcript 3 protein,GADD 153,GADD153,Growth Arrest and DNA Damage Inducible Protein 153,Growth arrest and DNA damage inducible protein GADD153,Growth arrest and DNA damage-inducible protein GADD153,MGC4154,CHOP Mouse (1E1)抗体 |
| Swissprot | P35638 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic Peptide of CHOP |
| Application | IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | IHC 1:100-200 |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Nucleus. |
| Clone No | Clone:1E1 |
|---|---|
| Isotype | IgG |
| Purification | Protein A purification |
| Conjugation | CHOP Mouse Monoclonal Antibody |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Background | This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. |
