Claudin 1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12455
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Claudin-1,Claudin1,CLD 1,CLD1,CLD1,CLDN 1,Cldn1,ILVASC,SEMP 1,SEMP1,Senescence associated epithelial membrane protein 1,Senescence associated epithelial membrane protein,Senescence-associated epithelial membrane protein,CLDN1抗体 |
| Swissprot | O95832 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human CLDN1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:3000;IHC,,1:100-1:300; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell junction, tight junction. Cell membrane. |
| Tissue specificity | Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. |
Images
Western Blot analysis of Hela cell using Claudin 1 Polyclonal Antibody at dilution of 1:1100
Immunohistochemistry of paraffin-embedded Human esophagus cancer using Claudin 1 Polyclonal Antibody at dilution of 1:150
Immunohistochemistry of paraffin-embedded Human cervical cancer using Claudin 1 Polyclonal Antibody at dilution of 1:150
客户发表文献
- 文献: Deep-fried Atractylodes lancea rhizome alleviates spleen deficiency diarrhea–induced short-chain fatty acid metabolic disorder in mice by remodeling the intestinal flora
样品类型: colon tissue - 文献: Characterisation of endogenous Claudin‐1 expression, motility and susceptibility to hepatitis C virus in CRISPR knock‐in cells
样品类型: Huh7.5.1 cell
