Claudin 3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12453
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | C7orf1,Claudin-3,Claudin3,CLD3,CLDN 3,Cldn3,Clostridium perfringens enterotoxin receptor 2,CPE R2,CPE receptor 2,CPE-R 2,CPE-receptor 2,CPETR 2,CPETR2,HRVP 1,HRVP1,Rat ventral prostate 1 like protein,Rat ventral prostate.1 protein homolog,RVP1,Ventral prostate.1 like protein,Ventral prostate.1 protein homolog,CLDN3抗体 |
| Swissprot | O15551 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human CLDN3 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. |
Images
Western Blot analysis of Human colon cancer tissue using Claudin 3 Polyclonal Antibody at dilution of 1:550
Immunohistochemistry of paraffin-embedded Human cervical cancer using Claudin 3 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human breast cancer using Claudin 3 Polyclonal Antibody at dilution of 1:25
