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COX6A2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19748

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms COX VIa M,COX6AH,COXVIAH,Cytochrome c oxidase polypeptide VIa heart,Cytochrome c oxidase subunit 6A2 mitochondrial,Cytochrome c oxidase subunit VIA muscle,Cytochrome c oxidase subunit VIa polypeptide 2,MS411,COX6A2抗体
    Swissprot Q02221
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human COX6A2
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.5mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion inner membrane
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.
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