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COX6B1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10074

宿主: Rabbit

反应性: H,M

应用: WB,IHC

  • 详情
  • Overview

    Synonyms COX 6B,COX VIb 1,COX VIb-1,COX6B,COX6B1,COXG,COXVIb1,CX6B1,Cytochrome c oxidase subunit 6B1,Cytochrome c oxidase subunit VIb,Cytochrome c oxidase subunit VIb isoform 1,cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous),Cytochrome c oxidase subunit Vib polypeptide 1,COX6B1抗体
    Swissprot P14854
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Recombinant protein of human COX6B1
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:1000-1:5000;IHC,,1:50-1:200;
    Concentration 0.6 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion intermembrane space.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.
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