COX6C Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17879
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | COX 6C,Cox6c,COX6C,Cytochrome c oxidase polypeptide VIc,Cytochrome c oxidase subunit 6C,cytochrome c oxidase subunit VIc,Cytochrome c oxidase subunit VIc preprotein,COX6C抗体 |
Swissprot | P09669 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human COX6C |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
Concentration | 0.7mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion inner membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. |
Images
Western blot analysis of HEPG2 HUVEC and NIH/3T3 cell Human heart tissue Mouse heart tissue PC-3 cell lysates using COX6C Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using COX6C Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using COX6C Polyclonal Antibody at dilution of 1:25(×200)