CREB2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-13942
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | Activating transcription factor 4,ATF 4,ATF4,ATF4 protein,ATF4,cAMP-dependent transcription factor ATF-4,cAMP-responsive element-binding protein 2,CREB 2,CREB-2,CREB2,Cyclic AMP dependent transcription factor ATF 4,Cyclic AMP response element binding protein 2,Cyclic AMP-dependent transcription factor ATF-4,Cyclic AMP-responsive element-binding protein 2,DNA binding protein TAXREB67,DNA-binding protein TAXREB67,Tax Responsive Enhancer Element B67,Tax-responsive enhancer element-binding protein 67,TaxREB67,TXREB,ATF4抗体 |
Swissprot | P18848 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human ATF4 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.7 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Cell membrane. Nucleus. Colocalizes with GABBR1 in hippocampal neuron dendritic membranes. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1.The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2).The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins.These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. |