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CRHR2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-16358

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms Corticotropin releasing hormone receptor 2,Corticotropin-releasing factor receptor 2,Corticotropin-releasing hormone receptor 2,CRF 2,CRF 2R,CRF R2,CRF RB,CRF-R-2,CRF-R2,CRF2,CRF2 receptor beta isoform,CRF2R,CRFR 2,CRFR-2,CRFR2,CRFR2,CRH 2R,CRH R2,CRH-R-2,CRH-R2,CRH2R,CRHR 2,Crhr2,HM CRF,CRHR2抗体
    Swissprot Q13324
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human CRHR2
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:200-1:1000;
    Concentration 0.4mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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