CRHR2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-16358
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | Corticotropin releasing hormone receptor 2,Corticotropin-releasing factor receptor 2,Corticotropin-releasing hormone receptor 2,CRF 2,CRF 2R,CRF R2,CRF RB,CRF-R-2,CRF-R2,CRF2,CRF2 receptor beta isoform,CRF2R,CRFR 2,CRFR-2,CRFR2,CRFR2,CRH 2R,CRH R2,CRH-R-2,CRH-R2,CRH2R,CRHR 2,Crhr2,HM CRF,CRHR2抗体 |
Swissprot | Q13324 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human CRHR2 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:200-1:1000; |
Concentration | 0.4mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |