CRKL Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13171
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Crk L,Crk like protein,Crk-like protein,Crkl,CRKL,Crkol,HGNC:2363 ,Oncogene CrkL,V crk avian sarcoma virus CT10 oncogene homolog like,v crk sarcoma virus CT10 oncogene homolog (avian) like,V crk sarcoma virus CT10 oncogene homolog avian like,CRKL抗体 |
| Swissprot | P46109 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human CRKL |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Endosome,Extracellular region or secreted,extracellular exosome |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. |
Images
Western Blot analysis of Lovo, A431, A549, hela, hepG2 and Raji cell, Mouse brain tissue using CRKL Polyclonal Antibody at dilution of 1:550
Immunohistochemistry of paraffin-embedded Human gastic cancer using CRKL Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CRKL Polyclonal Antibody at dilution of 1:25
