CXCL2/MIP-2 Polyclonal Antibody(Capture/Detector)
| 规格： | / 25μg / 100μg |
| 价格： | / 询价 / 询价 |
货号：AN003810P
货期：咨询
宿主: Rabbit
反应性: M,R
应用: ELISA Capture/Detector
Overview
| Synonyms | GRO;chemokine ligand;Scyb;C-X-C motif chemokine;CXCL;chemokine ligand 2;CINC2a;CINC-2a;C-X-C motif chemokine 2;GRO beta;GRO2;GRO2 oncogene|MGSA beta|melanoma growth stimulatory activity beta;GROB;Gro-beta;Growth-regulated protein beta;Macrophage Inflammatory Protein-2-alpha;melanoma growth stimulatory activity beta;MGSA-b;MGSA-beta;MIP2A;MIP-2a;MIP2-alpha;SCYB2.;Mip-2;Mip2;Scyb2;Cxcl2 |
| Swissprot | P10889 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant Mouse CXCL2/MIP-2 Protein expressed by E.coli |
| Application | ELISA Capture/Detector |
| Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS ,pH 7.4 |
| Background | CXCL2, also known as macrophage inflammatory protein 2-alpha (MIP2-alpha), is a member of CXC chemokine family that binds to CXC chemokine receptor 2 (CXCR2). CXCL2 is mainly produced by macrophages, endothelial cells, epithelial cells and tumor cells. CXCL2 plays important roles in various biological progresses such as angiogenesis, inflammation, immune response and cancer biological behaviors. Under inflammatory conditions in CNS, microglia and astrocytes may secrete CXCL2 as well as other chemokines, which induces chemotaxis and infiltration of circulatory neutrophils. Indeed, previous studies suggest that CXCL2 is involved in Alzheimer disease, multiple sclerosis and brain ischemia. |
