CXCL4 Polyclonal Antibody
规格: | / 20μL / 50μL / 100μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40572
宿主: Rabbit
反应性: H
应用: WB
Overview
Synonyms | CXCL4,SCYB4,Plateletfactor4,C-X-Cmotifchemokine4,PF-4,Iroplact,Oncostatin-AEndothelialcellgrowthinhibito,PF4 |
Swissprot | P02776 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant Human CXCL4 protein expressed by E.coli. |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:1000-2000; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted |
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
Background | CXCL4/PF4 is a secreted chemokine that is expressed by megakaryocytes and restrains the coagulation cascade. It is released by activated platelets and regulates Thrombin/Thrombomodulin complexes, activated Protein C (APC), Coagulation Factor Xa, and Fibrin. The anticoagulant heparin neutralizes CXCL4 procoagulant effects. Complexes of heparin and CXCL4 trigger antibody formation that causes the pathological syndrome HITT |