CYB5R3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19777
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | B5R,Cyb5r3,Cytochrome b5 reductase 3,Cytochrome b5 reductase,DIA1,Diaphorase 1,Diaphorase-1,NADH cytochrome b5 reductase 3,NADH-cytochrome b5 reductase 3 membrane-bound form,NADH-cytochrome b5 reductase 3 soluble form,NB5R3,OTTHUMP00000028761,OTTHUMP00000198435,OTTHUMP00000198574,OTTHUMP00000198662,OTTHUMP00000198665,CYB5R3抗体 |
| Swissprot | P00387 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human CYB5R3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 1.2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endoplasmic reticulum membrane. Mitochondrion outer membrane and Cytoplasm. Produces the soluble form found in erythrocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | CYB5R3,also named as DIA1 and B5R,belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. It plays an essential role in the mitochondrial metabolism by its contribution to cellular redox homeostasis. Overstimulation of CYB5R3 associated with lipid rafts can account for the overshot of plasma membrane-focalized superoxide anion production that triggers the entry of CGN in the irreversible phase of apoptosis. |
