CYCS Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70033
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC,IF
Overview
Synonyms | Cytochrome C, Somatic,CYC,Cytochrome C,THC4,HCS.,CYCS抗体 |
Swissprot | P99999,P62898,P62897 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),IF |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:500-1:1000;IF,,1:200-1:800; |
Concentration | 1.5 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion |
Tissue specificity | Highest expression level in heart |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy. |
Images
Western Blot analysis of various samples using CYCS Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using CYCS Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of paraffin-embedded mouse kidney using CYCS Polyclonal Antibody at dilution of 1:500.
Immunofluorescence analysis of paraffin-embedded mouse liver using CYCS Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded Human Heart using CYCS Polyclonal Antibody(Elabscience® Product Detected by Lifespan).
客户发表文献
- 文献: and caspase 3 levels in rats with myocardial infarction
样品类型: Tissue