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DAAM1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-13182

宿主: Rabbit

反应性: H,M

应用: WB,IHC

  • 详情
  • 文献(1)
  • Overview

    Synonyms DAAM 1,Dishevelled associated activator of morphogenesis 1,FLJ41657,KIAA0666,DAAM1抗体
    Swissprot Q9Y4D1
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Synthetic peptide of human DAAM1
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:200-1:1000;IHC,,1:50-1:200;
    Concentration 1.2 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasmic. Note: Perinuclear.
    Tissue specificity Expressed in all tissues examined.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes.The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity.A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement.The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex.

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