DCP1A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14933
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | DCP1 decapping enzyme homolog A,Dcp1a,DCP1A,Decapping enzyme hDcp1a,Decapping mRNA 1A,HSA275986,mRNA decapping enzyme 1A,mRNA-decapping enzyme 1A,Nbla00360,Putative protein product of Nbla00360,Smad4 interacting transcriptional co activator,Smad4-interacting transcriptional co-activator,Smad4-interacting transcriptional co-activator,SMAD4IP1,SMIF,Transcription factor SMIF,DCP1A抗体 |
| Swissprot | Q9NPI6 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human DCP1A |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:100-1:300; |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>P-body. Nucleus. Co-localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4. |
| Tissue specificity | Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Decapping is a key step in general and regulated mRNA decay.The protein encoded by this gene is a decapping enzyme.This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons.This protein also participates in the TGF-beta signaling pathway. |
Images
Western Blot analysis of Hela cell using DCP1A Polyclonal Antibody at dilution of 1:1100
Immunohistochemistry of paraffin-embedded Human cervical cancer using DCP1A Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human colon cancer using DCP1A Polyclonal Antibody at dilution of 1:50
