DLG4 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70135
宿主: Rabbit
反应性: M,R
应用: WB,IHC
Overview
| Synonyms | Discs large homolog 4,Disks large homolog 4,DLG 4,Dlg4,DLG4,FLJ97752,FLJ98574,Human post synaptic density protein 95,Post synaptic density protein 95,Postsynaptic density protein 95,PSD 95,PSD-95,PSD95,SAP 90,SAP-90,SAP90,Synapse associated protein 90,Synapse-associated protein 90,Tax interaction protein 15,DLG4抗体 |
| Swissprot | Q62108,P31016 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse PSD95 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:1000;IHC,,1:100-1:200; |
| Concentration | 300 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, axon. Cell junction, synapse. High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells. |
| Tissue specificity | Highly expressed in CA1 stratum oriens and stratum radiatum hippocampal neurons.Highest expression level in cerebellum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. |
Images
Western Blot analysis of various samples using DLG4 Polyclonal Antibody at dilution of 1:750.
Immunohistochemistry analysis of paraffin-embedded mouse brain using DLG4 Polyclonal Antibody at dilution of 1:100.
Immunohistochemistry analysis of paraffin-embedded rat brain using DLG4 Polyclonal Antibody at dilution of 1:100.
