ECH1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18979
宿主: Rabbit
反应性: H,R
应用: WB,IHC
Overview
Synonyms | 4)-dienoyl-CoA isomerase,5)-Delta(2,Delta(3 5) Delta(2 4) dienoyl CoA isomerase,Delta(3 5) Delta(2 4) dienoyl CoA isomerase mitochondrial,Delta(3,Delta3 5 delta2 4 dienoyl CoA isomerase,Dienoyl CoA isomerase,ECH 1,Ech1,ECH1,Enoyl Coenzyme A hydratase 1,Enoyl Coenzyme A hydratase 1 peroxisomal,HPXEL,mitochondrial,MS1034,Peroxisomal enoyl CoA hydratase 1,Peroxisomal enoyl coenzyme A hydratase like protein,ECH1抗体 |
Swissprot | Q13011 |
Source | Rabbit |
Reactivity | Human,Rat |
Immunogen | Fusion protein of human ECH1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
Concentration | 0.6mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion. Peroxisome. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. |