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ECH1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-52890

宿主: Rabbit

反应性: H,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms 4)-dienoyl-CoA isomerase,5)-Delta(2,Delta(3 5) Delta(2 4) dienoyl CoA isomerase,Delta(3 5) Delta(2 4) dienoyl CoA isomerase mitochondrial,Delta(3,Delta3 5 delta2 4 dienoyl CoA isomerase,Dienoyl CoA isomerase,ECH 1,Ech1,ECH1,Enoyl Coenzyme A hydratase 1,Enoyl Coenzyme A hydratase 1 peroxisomal,HPXEL,mitochondrial,MS1034,Peroxisomal enoyl CoA hydratase 1,Peroxisomal enoyl coenzyme A hydratase like protein,ECH1抗体
    Swissprot Q13011
    Source Rabbit
    Reactivity Human,Rat
    Immunogen Fusion protein of human ECH1
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:50-1:300;
    Concentration 0.9mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion. Peroxisome.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
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