EDARADD Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52310
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Cr,Crinkled homolog,ectodysplasia A receptor associated death domain,Ectodysplasin-A receptor-associated adapter protein,ED3,EDA3,EDAD,EDAR associated death domain,EDAR-associated death domain protein,EDARADD,Protein crinkled homolog,EDARADD抗体 |
| Swissprot | Q8WWZ3 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Full length fusion protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:35-1:200 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands.The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives.This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth.Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways.Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
