EDG3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12921
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | EDG 3,EDG3,Endothelial differentiation G protein coupled receptor 3,Endothelial differentiation G-protein coupled receptor 3,Endothelial differentiation gene 3,Endothelial differentiation sphingolipid G protein coupled receptor 3,FLJ37523,FLJ93220,G protein coupled receptor endothelial differentiation gene 3,LPB 3,LPB3,MGC71696,OTTHUMP00000215691,S1P receptor 3,S1P receptor Edg 3,S1P receptor Edg-3,S1P receptor EDG3,S1P3,S1pr3,S1PR3,Sphingosine 1 phosphate receptor 3,Sphingosine 1 phosphate receptor Edg 3,Sphingosine 1 phosphate receptor Edg3,Sphingosine 1-phosphate receptor 3,Sphingosine 1-phosphate receptor Edg-3,S1PR3抗体 |
| Swissprot | Q99500 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human S1PR3 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Tissue specificity | Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
