EIF2 alpha Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-31295
宿主: Rabbit
反应性: H,M,R,Mk
应用: WB,IHC-p,IF
Overview
| Synonyms | EIF 2 alpha,EIF 2,EIF 2A,EIF 2alpha,eIF-2-alpha,eIF-2A,EIF-2alpha,EIF2 alpha,EIF2,EIF2A,EIF2S1,Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa,Eukaryotic translation initiation factor 2 subunit 1 alpha,Eukaryotic translation initiation factor 2 subunit 1,Eukaryotic translation initiation factor 2 subunit alpha,IF2A,eIF2α抗体 |
| Swissprot | P05198 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat,Monkey |
| Immunogen | Synthesized peptide derived from human eIF2α around the non-phosphorylation site of Ser51. |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:50-1:200; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic granule. The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins. |
Images
Western Blot analysis of various cells using EIF2 alpha Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using EIF2 alpha Polyclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Rat kidney tissue using EIF2 alpha Polyclonal Antibody at dilution of 1:200.
