ENAH Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18029
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | ENAH, Actin Regulator,MENA,Mammalian Enabled Variant 11a,Mammalian Enabled Variant Pan,Enabled Homolog (Drosophila),Protein Enabled Homolog.,ENAH抗体 |
| Swissprot | Q8N8S7 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human ENAH |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 1.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Cytoplasm>cytoskeleton. Cell projection>lamellipodium. Cell projection>filopodium. Cell junction>synapse. Cell junction>focal adhesion. Targeted to the leading edge of lamellipodia and filopodia by MRL family members. Colocalizes at filopodial tips with a number of other proteins including vinculin and zyxlin. Colocalizes with N-WASP at the leading edge. Colocalizes with GPHN and PFN at synapses. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the enabled/ vasodilator-stimulated phosphoprotein. Members of this gene family are involved in actin-based motility. This protein is involved in regulating the assembly of actin filaments and modulates cell adhesion and motility. Alternate splice variants of this gene have been correlated with tumor invasiveness in certain tissues and these variants may serve as prognostic markers. A pseudogene of this gene is found on chromosome 3.ENAH (Enabled Homolog (Drosophila)) is a Protein Coding gene. Among its related pathways are TCR signaling (REACTOME) and Innate Immune System. GO annotations related to this gene include actin binding and WW domain binding. An important paralog of this gene is EVL. |
