ENPP2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19626
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | ATX,ATX X,Autotaxin,Autotaxin t,E NPP 2,E-NPP 2,Ectonucleotide pyrophosphatase/phosphodiesterase 2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2,Enpp2,ENPP2,Extracellular lysophospholipase D,FLJ26803,LysoPLD,NPP2,PD IALPHA,PDNP2,Phosphodiesterase I alpha,Phosphodiesterase I/nucleotide pyrophosphatase 2,Plasma lysophospholipase D,ENPP2抗体 |
| Swissprot | Q13822 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human ENPP2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. Secreted by most body fluids including serum and CSF. Also by adipocytes and numerous cancer cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. |
