Ephrin A1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14062
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | B61,ECKLG,EFL 1,EFL1,EFNA 1,Efna1,EFNA1,EPH related receptor tyrosine kinase ligand 1,EPH-related receptor tyrosine kinase ligand 1,Ephrin-A1,Ephrin-A1,secreted form,EphrinA1,EPLG 1,EPLG1,Immediate early response protein B61,LERK 1,LERK-1,LERK1,Ligand of eph related kinase 1,OTTHUMP00000033242,OTTHUMP00000033271,secreted form,TNF alpha-induced protein 4,TNFAIP 4,TNFAIP4,Tumor necrosis factor alpha induced protein 4,Tumor necrosis factor alpha-induced protein 4,EFNA1抗体 |
| Swissprot | P20827 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human EFNA1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:150 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. |
| Tissue specificity | Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level). |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. |
