ERK 2 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70240
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | ERK 2,ERK,ERK-2,ERT1,Extracellular Signal Regulated Kinase 2,Extracellular signal-regulated kinase 2,MAP kinase 1,MAP kinase 2,MAP kinase isoform p42,MAPK 1,MAPK 2,Mapk1,MAPK2,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 2,MK01,P38,P40,P41,p42-MAPK,P42MAPK,PRKM1,PRKM2,protein kinase,mitogen-activated,1,protein kinase,mitogen-activated,2,protein tyrosine kinase ERK2,ERK 2抗体 |
| Swissprot | P28482,P63085,P63086 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse ERK2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 100 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, Cytoskeleton, Membrane, Nucleus |
| Tissue specificity | Highest expression level in putamen |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a member of the MAP kinase family.MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.The activation of this kinase requires its phosphorylation by upstream kinases.Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity.The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
