EXD2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18841
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | 4930539P14Rik,C14orf114,C85658,DKFZp781A0133,DKFZp781L15100,Exd2,EXD2,EXDL2,Exonuclease 3''-5'' domain-containing protein 2,Exonuclease 3''-5'' domain-like-containing protein 2,exonuclease 3'-5' domain-like 2,FLJ10738,RGD1311087,EXD2抗体 |
Swissprot | Q9NVH0 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Fusion protein of human EXD2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
Concentration | 0.96mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. |
Images
Western blot analysis of Mouse brain tissue and Human cerebrum tissue lysates using EXD2 Polyclonal Antibody at dilution of 1:700
Immunohistochemistry of paraffin-embedded Human tonsil tissue using EXD2 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using EXD2 Polyclonal Antibody at dilution of 1:55(×200)