FGB Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-15039
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | Epididymis secretory sperm binding protein Li 78p,FGB,FIBB,Fibrinogen B beta polypeptide,Fibrinogen beta chain,Fibrinogen beta polypeptide chain,Fibrinopeptide B,HEL S 78p,Liver regeneration-related protein LRRG036/LRRG043/LRRG189,MGC104327,MGC120405,OTTHUMP00000197066,FGB抗体 |
Swissprot | P02675 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human FGB |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:1000-1:5000; |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted. |
Tissue specificity | Detected in blood plasma (at protein level). |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. |
Images
Western Blot analysis of Mouse heart tissue using FGB Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human colon cancer using FGB Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human cervical cancer using FGB Polyclonal Antibody at dilution of 1:20