FGF1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12293
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Acidic fibroblast growth factor,aFGF,Beta endothelial cell growth factor,Beta-endothelial cell growth factor,ECGF,ECGF beta,ECGF-beta,ECGFA,ECGFB,Endothelial Cell Growth Factor alpha,Endothelial Cell Growth Factor beta,FGF 1,FGF alpha,Fgf1,FGF1,FGFA,Fibroblast Growth Factor 1 Acidic,Fibroblast growth factor 1,GLIO703,HBGF 1,HBGF-1,HBGF1,Heparin binding growth factor 1,Heparin binding growth factor 1 precursor,Heparin-binding growth factor 1,FGF1抗体 |
| Swissprot | P05230 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human FGF1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. Cytoplasm. Cytoplasm>cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1. |
| Tissue specificity | Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.FGF1 Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. |
