FOXO3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-31469
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC-p,IF
Overview
| Synonyms | AF6q21,AF6q21 protein,DKFZp781A0677,FKHR2,FKHRL 1,FKHRL1,FKHRL1P2,Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1,Forkhead box O3,Forkhead box O3A,Forkhead box protein O3,Forkhead box protein O3A,Forkhead Drosophila homolog of in rhabdomyosarcoma like 1,Forkhead homolog (rhabdomyosarcoma) like 1,Forkhead in rhabdomyosarcoma like 1,Forkhead in rhabdomyosarcoma-like 1,FOX O3A,FOXO2,foxo3,FOXO3,FOXO3A,MGC12739,MGC31925,FoxO3A抗体 |
| Swissprot | O43524 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from human FoxO3A around the non-phosphorylation site of Ser253. |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:200-1:1000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors. |
| Tissue specificity | Ubiquitous. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. |
