FOXO4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53430
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | AFX,AFX1,Afxh,ALL1-fused gene from X chromosome,Fork head domain transcription factor AFX1,Forkhead box O4,Forkhead box protein O4,FOXO 4,Foxo4,FOXO4,MGC117660,MGC120490,Mixed lineage leukemia,translocated to,7,MLLT7,Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog,Drosophila),translocated to,7,Myeloid/lymphoid or mixed lineage leukemia,translocated to,7,RGD1561201,FOXO4抗体 |
| Swissprot | P98177 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human FOXO4 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:350 |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. |
