FXYD1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14740
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | FXYD domain containing ion transport regulator 1,Phospholemman,PLM,FXYD1抗体 |
| Swissprot | O00168 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human FXYD1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane; single-pass type I membrane protein |
| Tissue specificity | Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids.The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator.Mouse FXYD5 has been termed RIC (Related to Ion Channel).FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme.FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. |
Images
Western Blot analysis of Mouse heart tissue using FXYD1 Polyclonal Antibody at dilution of 1:1290
Immunohistochemistry of paraffin-embedded Human tonsil using FXYD1 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human colon cancer using FXYD1 Polyclonal Antibody at dilution of 1:60
