GLUT-1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70090
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity),CSE,DYT17,DYT18,DYT9,EIG12,erythrocyte/brain,Erythrocyte/hepatoma glucose transporter,facilitated glucose transporter member 1,Glucose transporter 1,Glucose transporter type 1,Glucose transporter type 1,erythrocyte/brain,GLUT,GLUT-1,GLUT1,GLUT1DS,GLUTB,GT1,GTG1,Gtg3,GTR1,HepG2 glucose transporter,HTLVR,Human T cell leukemia virus (I and II) receptor,MGC141895,MGC141896,PED,RATGTG1,Receptor for HTLV 1 and HTLV 2,SLC2A1,Solute carrier family 2 (facilitated glucose transporter),member 1,Solute carrier family 2,Solute carrier family 2,facilitated glucose transporter member 1,GLUT-1抗体 |
| Swissprot | P11166,P17809,P11167 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse GLUT1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:600 |
| Concentration | 73 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane |
| Tissue specificity | Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.Highest expression level in pigmented layer of retina. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | GLUT1,also known as SLC2A1,is an ubiquitously expressed glucose transporter and responsible for the basal level of glucose uptake in most cell types. Human erythrocytes express the highest level of the GLUT1. Defects in SLC2A1 are the cause of GLUT1 deficiency syndrome type 1 and type 2. High expression of GLUT1 has been reported to be a reliable immunohistochemical marker for juvenile hemangiomas. GLUT1 protein may appear as two or more distinct forms among 43 kDa to 55 kDa due to the different glycosylation state. And the conversion of highly glycosylated form of GLUT1 to less glycosylated form has been reported to correlate to differentiation. (8263524,23302780) |
Images
Immunohistochemistry analysis of paraffin-embedded human brain using GLUT-1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Mouse brain using GLUT-1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Rat brain using GLUT-1 Polyclonal Antibody at dilution of 1:300.
